Use a lag time for clearance?

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Fernando
Posts: 3
Joined: Wed Aug 27, 2014 7:48 am

Use a lag time for clearance?

Post by Fernando » Thu Mar 09, 2017 6:36 am

Hi all!!

I´m modelling blood and urine concentrations of a drug in mice. Samples are taken from blood and bladder with an intensive sampling.
My problem is that I have continous accummulation in bladder and then a discharge. So, I think that the best way to model this, is to set a lag in the clearance to mimick the bladder discharge.
I don´t know if I´m right

Many thanks in advance.
Fernando.

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